Metenolone Acetate (Primo A – 100mg – 50 Tabs

INTRODUCTION :
Metenolone Acetate (Primo A – 100mg – 50 Tabs

Molecular Weight: 344.495 g/mol
Active Ingredient: Methenolone acetate
Dosage Form: Tablet
Route: Oral
DOSAGE : Adult male: 50 -75 mg per day, Adult females: 25 ? 50 mg per day

DESCRIPTION

Primobolan (Methenolone acetate) is a synthetic, orally active anabolic-androgenic steroid
and dihydrotestosterone (DHT) derivative. It can be used for the treatment of bone marrow
disease and anemia. Methenolone acetate is known for its higher therapeutic efficiency and
lower hepatic toxicity compared with its 17 alpha- alkylated analogs. Methenolone cannot
aromatase to estrogen, reducing estrogenic side effects, and has a favorable safety profile
among anabolic agents.

CLINICAL PHARMACOLOGY

Anabolic steroids are synthetic derivatives of testosterone. Certain clinical effects and
adverse reactions demonstrate the androgenic properties of these drugs. Complete
dissociation of anabolic and androgenic effects has not been achieved. The actions of
anabolic steroids are thus similar to those of male sex hormones. Anabolic steroids suppress
the gonadotropic functions of the pituitary and may exert a direct effect upon the testes.
During exogenous administration of anabolic androgens, endogenous testosterone release
is inhibited through inhibition of pituitary luteinizing hormone (LH). At large doses,
spermatogenesis may be suppressed through feedback inhibition of pituitary folliclestimulating hormone (FSH). Methenolone acts upon the androgen receptor stimulating
anabolism through increased nitrogen retention and protein synthesis in muscle tissue.
Methenolone acetate in a single dose pharmacokinetic study has demonstrated a mean
elimination half-life of 6 days.

INDICATIONS

As an alternate or adjunctive therapy in patients for the promotion of weight gain muscular
atrophy associated with extensive surgery, infections, long term hospitalization, or severe
trauma. To compensate for protein catabolism consequent to corticosteroid therapy.

DOSAGE AND ADMINISTRATION

Adult male: 50 -75 mg per day, Adult females: 25 ? 50 mg per day for a duration of 4 to 6
weeks. It is not recommended to exceed the dosage of 100 ? 150 mg per day for adult
males.